Proposed Diagnostic Criteria for the Brugada Syndrome

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Proposed diagnostic criteria for the Brugada syndrome.

Asyndrome characterized by ST-segment elevation in right precordial leads (V1 to V3) that is unrelated to ischemia, electrolyte disturbances, or obvious structural heart disease was reported as early as 1953,1 but was first described as a distinct clinical entity associated with a high risk of sudden cardiac death in 1992.2–4 The Brugada syndrome is a familial disease that displays an autosomal...

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Proposed diagnostic criteria for the Brugada syndrome: consensus report.

Brugada, Pedro Brugada, Domenico Corrado, Richard N.W. Hauer, Robert S. Kass, Arthur A.M. Wilde, Charles Antzelevitch, Martin Borggrefe, Josep Brugada, Ramón Proposed Diagnostic Criteria for the Brugada Syndrome : Consensus Report ISSN: 1524-4539 Copyright © 2002 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart A...

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[Diagnostic criteria for the Brugada syndrome: can they be improved?].

INTRODUCTION Diagnosis of Brugada syndrome (BS) currently requires documentation of a characteristic repolarization pattern (type 1 Brugada ECG). Mutations in the SCN5A gene, which codes for sodium channel Na(v) 1.5, are found in 38% of familial cases of BS. Sodium current dysfunction negatively affects the cardiac fast response action potential, particularly in atrial and ventricular myocytes ...

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The Brugada syndrome: diagnostic criteria and cellular mechanisms.

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2002

ISSN: 0195-668X

DOI: 10.1053/euhj.2002.3382